Psoriasis and the association with Type 2 Diabetes
Psoriasis is a common immune-mediated disease of the skin characterized by inflammatory and hyper proliferative changes. Now considered a systemic disorder, psoriasis affects populations all over the world, with an estimated prevalence of 2.2?2.6% in the United States. Psoriasis involves the interaction of genetic predisposition, immune response, and environmental risk factors such as smoking, alcohol intake, and obesity.
Diabetes has been a major public health concern in the United States, with a prevalence of 8.3% in 2010. The prevalence of co-conditions, such as insulin resistance, metabolic syndrome, and type 2 diabetes associated with psoriasis has gained interest in recent years.
Prospective studies have provided further evidence that individuals developing psoriasis at a younger age are at a significantly higher risk of Type 2 Diabetes. This finding further shows that psoriasis is a systemic inflammatory disorder. The suggested association demonstrating psoriasis as a risk predictor for Type 2 Diabetes could hold general public health significance.